Hochstetter, A. and Pfohl, T. (2016) Motility, force generation, and energy consumption of unicellular parasites. Trends in Parasitology, 32(7), pp. 531-541. (doi: 10.1016/j.pt.2016.04.006) (PMID:27157805)
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Abstract
Motility is a key factor for pathogenicity of unicellular parasites, enabling them to infiltrate and evade host cells, and perform several of their life-cycle events. State-of-the-art methods of motility analysis rely on a combination of optical tweezers with high-resolution microscopy and microfluidics. With this technology, propulsion forces, energies, and power generation can be determined so as to shed light on the motion mechanisms, chemotactic behavior, and specific survival strategies of unicellular parasites. With these new tools in hand, we can elucidate the mechanisms of motility and force generation of unicellular parasites, and identify ways to manipulate and eventually inhibit them.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Hochstetter, Dr Axel |
| Authors: | Hochstetter, A., and Pfohl, T. |
| College/School: | College of Science and Engineering > School of Engineering |
| Journal Name: | Trends in Parasitology |
| Publisher: | Elsevier |
| ISSN: | 1471-4922 |
| ISSN (Online): | 1471-5007 |
| Published Online: | 03 May 2016 |
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