Specificity of New Diagnostic Criteria for Left Ventricular Hypertrophy

Clark, E. and Macfarlane, P. (2018) Specificity of New Diagnostic Criteria for Left Ventricular Hypertrophy. In: Computing in Cardiology 2017, Rennes, France, 24-27 Sept 2017, (doi: 10.22489/CinC.2017.013-116)

161114.pdf - Accepted Version



The aim of this study was to assess the recent publication of new Peguero/Lo Presti (P-LP) ECG criteria for left ventricular hypertrophy (LVH) which purported to have a higher sensitivity than commonly used existing criteria but with no significant loss of specificity (≥90%) compared to the other LVH criteria. ECGs from 1496 apparently healthy adults from the Glasgow normals ECG database were used to assess specificity. The new P-LP criteria (maximum S amplitude in any lead plus S amplitude in V4) were assessed together with the long established Sokolow-Lyon and Cornell criteria (the latter being sex based) for LVH. The Glasgow criteria were also assessed. The specificity of the new P-LP criteria were found to be exceptionally poor in younger persons, being 50% and 76% in males and females < 30 years respectively increasing to 83% and 89% respectively in the group ≥ 50 years. The Cornell criterion specificity exceeded 90% at all ages in both sexes. New diagnostic criteria for LVH must be age and sex dependent and ideally should undergo a thorough evaluation of specificity on a large database of apparently healthy individuals from both sexes aged 18 years and over before publication.

Item Type:Conference Proceedings
Glasgow Author(s) Enlighten ID:Macfarlane, Professor Peter and Clark, Mrs Elaine
Authors: Clark, E., and Macfarlane, P.
College/School:College of Medical Veterinary and Life Sciences > School of Health & Wellbeing > Robertson Centre
Copyright Holders:Copyright © 2017 IEEE
Publisher Policy:Reproduced in accordance with the copyright policy of the publisher

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