Marsh, S., Paul, J. , McLeod, H.L. and Brown, R. (2008) Ethnic considerations in pharmacogenetic studies - In reply. Journal of Clinical Oncology, 26(10), pp. 1767-1768. (doi: 10.1200/JCO.2007.15.8212)
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Abstract
Branford et al correctly highlight that ethnic variability in allele frequencies can be a major source of variability between pharmacogenetic studies. Indeed, as we discuss in the original publication,1 population differences along with other differences between studies (eg, sample size, tumor type, and treatment regimen) are all possible causes for the lack of replication of previous findings.
| Item Type: | Articles (Letter) |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Paul, Mr James |
| Authors: | Marsh, S., Paul, J., McLeod, H.L., and Brown, R. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Cancer Sciences |
| Journal Name: | Journal of Clinical Oncology |
| ISSN: | 0732-183X |
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