MMP-2 and sTNF-R1 variability in patients with essential hypertension: 1-year follow-up study

Carpena, N. et al. (2012) MMP-2 and sTNF-R1 variability in patients with essential hypertension: 1-year follow-up study. ISRN Cardiology, 2012, 501894. (doi: 10.5402/2012/501894) (PMID:23008783) (PMCID:PMC3449115)

[img]
Preview
Text
159754.pdf - Published Version
Available under License Creative Commons Attribution.

1MB

Abstract

The aim of this study is to analyze MMP-2 and sTNF-R1 variability, potent predictors of cardiovascular events, in stable hypertensive patients during a 12-month followup. 234 asymptomatic patients (age 6 0 ± 1 3 , 136 male) out of 252 patients with essential hypertension were followed up. MMP-2 and sTNF-R1 were measured at baseline and after 12 months (stage I). To compare MMP-2 and sTNF-R1 levels over time interval, we used the statistical method of Bland-Altman. MMP-2 and sTNF-R1 reproducibility was good in our patients for the two intervals with a coefficient of reproducibility of 8.2% and 11.3%, respectively. The percentages of patients within 1.96 × standard deviation of the mean were 93.6% and 92.7%. An elevated coefficient of correlation was obtained for MMP-2, basal versus stage I (

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Carpena Garcia, Miss Nuria
Authors: Carpena, N., Roselló-Lletí, E., Calabuig, J. R., Tarazón, E., González-Juanatey, J. R., Martínez-Dolz, L., Salvador, A., Grigorian, L., Orosa, P., Portolés, M., and Rivera, M.
College/School:College of Medical Veterinary and Life Sciences > School of Infection & Immunity
Journal Name:ISRN Cardiology
Publisher:Hindaawi
ISSN:2090-5599
ISSN (Online):2090-5599
Copyright Holders:Copyright © 2012 Nuria Carpena et al.
First Published:First published in ISRN Cardiology 2012:501894
Publisher Policy:Reproduced under a Creative Commons License

University Staff: Request a correction | Enlighten Editors: Update this record