Constitutive laws with damage effect for the human great saphenous vein

Li, W. (2018) Constitutive laws with damage effect for the human great saphenous vein. Journal of the Mechanical Behavior of Biomedical Materials, 81, pp. 202-213. (doi: 10.1016/j.jmbbm.2018.02.027) (PMID:29529591)

[img]
Preview
Text
159498.pdf - Accepted Version
Available under License Creative Commons Attribution Non-commercial No Derivatives.

1MB

Abstract

Strain energy-based constitutive laws with damage effect were proposed by using existing both uniaxial tensile test and tubular biaxial inflation test data on the human great saphenous vein (GSV) segments. These laws were applied into GSV coronary artery bypass grafts (CABG) by employing a thin-walled vessel model to evaluate their passive biomechanical performance under coronary artery physiological conditions at a fixed axial pre-stretch. At a peak systolic pressure in 100-150 mmHg, a 20-33% GSV diameter dilation was predicted with the law based on tubular biaxial inflation test data and agreed well with 25% dilation in clinical observation in comparison with as small as 2-4% dilation estimated with the law based on uniaxial tensile test data. The constitutive law generated by tubular biaxial inflation test data was mostly suitable for GSV CABG under coronary artery physiological conditions than that based on uniaxial tensile test results. With these laws, the fibre ultimate stretch was extracted from uniaxial tensile test data and the structural sub-failure/damage threshold of 1.0731 was decided for the human GSV. GSV fibres could exhibit damage effect but unlikely undergo a structure failure/break, suggesting a damage factor might exist during CABG arterialization. The damage in GSV tissue might initiate or contribute to early remodelling of CABG after implantation. [Abstract copyright: Copyright © 2018 Elsevier Ltd. All rights reserved.]

Item Type:Articles
Keywords:Collagen fibre orientation, constitutive law, coronary artery bypass graft, damage model, great saphenous vein, strain energy function.
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Li, Dr Wenguang
Authors: Li, W.
College/School:College of Science and Engineering > School of Mathematics and Statistics > Mathematics
Journal Name:Journal of the Mechanical Behavior of Biomedical Materials
Publisher:Elsevier
ISSN:1751-6161
ISSN (Online):1878-0180
Published Online:23 February 2018
Copyright Holders:Copyright © 2018 Elsevier Ltd.
First Published:First published in Journal of the Mechanical Behavior of Biomedical Materials 81: 202-213
Publisher Policy:Reproduced in accordance with the publisher copyright policy

University Staff: Request a correction | Enlighten Editors: Update this record