Munje, C. and Copland, M. (2018) Exploring stem cell heterogeneity in chronic myeloid leukemia. Trends in Cancer, 4(3), pp. 167-169. (doi: 10.1016/j.trecan.2017.12.001) (PMID:29506666)
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Abstract
Until very recently, understanding the complexity of the stem cell (SC) compartment in both normal and leukemic hematopoiesis has been challenging due to the inability to separate and study normal and leukemic SCs at the single-cell level. Recent advances in cell-sorting techniques and single-cell technologies now make this possible, with the identification of a population of highly quiescent chronic myeloid leukemia (CML) SCs that is enriched following therapy with tyrosine kinase inhibitors (TKIs).
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Munje, Dr Chinmay and Copland, Professor Mhairi |
| Authors: | Munje, C., and Copland, M. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Cancer Sciences |
| Journal Name: | Trends in Cancer |
| Publisher: | Elsevier |
| ISSN: | 2405-8033 |
| ISSN (Online): | 2405-8033 |
| Published Online: | 21 December 2017 |
| Copyright Holders: | Copyright © 2017 Elsevier |
| First Published: | First published in Trends in Cancer 4(3):167-169 |
| Publisher Policy: | Reproduced in accordance with the copyright policy of the publisher |
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