Interatrial shunt devices for heart failure with normal ejection fraction: a technology update

Cuthbert, J. J., Pellicori, P. and Clark, A. L. (2017) Interatrial shunt devices for heart failure with normal ejection fraction: a technology update. Medical Devices: Evidence and Research, 10, pp. 123-132. (doi:10.2147/mder.s113105) (PMID:28652826) (PMCID:PMC5476655)

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Abstract

Heart failure with normal ejection fraction (HeFNEF) accounts for ~50% of heart failure admissions. Its pathophysiology and diagnostic criteria are yet to be defined clearly which may hinder the search for effective treatments. The clinical hallmark of HeFNEF is exertional breathlessness, often due to an abnormal increase in left atrial pressure during exercise. Creation of an interatrial communication to offload the left atrium is a possible therapeutic approach. There are two percutaneously delivered devices currently under investigation which are discussed in this review.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Pellicori, Dr Pierpaolo
Authors: Cuthbert, J. J., Pellicori, P., and Clark, A. L.
College/School:College of Medical Veterinary and Life Sciences > Institute of Health and Wellbeing > Robertson Centre
Journal Name:Medical Devices: Evidence and Research
Publisher:Dove Medical Press
ISSN:1179-1470
ISSN (Online):1179-1470
Published Online:02 June 2017
Copyright Holders:Copyright © 2017 Cuthbert et al.
First Published:First published in Medical Devices: Evidence and Research 10:123-132
Publisher Policy:Reproduced under a Creative Commons License

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