Fast selective trapping and release of picoliter droplets in a 3D microfluidic PDMS multi-trap system with bubbles

Rambach, R. W., Biswas, P., Yadav, A., Garstecki, P. and Franke, T. (2018) Fast selective trapping and release of picoliter droplets in a 3D microfluidic PDMS multi-trap system with bubbles. Analyst, 143(4), pp. 843-849. (doi:10.1039/c7an01100h) (PMID:29234760)

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Abstract

The selective manipulation and incubation of individual picoliter drops in high-throughput droplet based microfluidic devices still remains challenging. We used a surface acoustic wave (SAW) to induce a bubble in a 3D designed multi-trap polydimethylsiloxane (PDMS) device to manipulate multiple droplets and demonstrate the selection, incubation and on-demand release of aqueous droplets from a continuous oil flow. By controlling the position of the acoustic actuation, individual droplets are addressed and selectively released from a droplet stream of 460 drops per s. A complete trapping and releasing cycle can be as short as 70 ms and has no upper limit for incubation time. We characterize the fluidic function of the hybrid device in terms of electric power, pulse duration and acoustic path.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Biswas, Ms Preetika and Franke, Professor Thomas
Authors: Rambach, R. W., Biswas, P., Yadav, A., Garstecki, P., and Franke, T.
College/School:College of Science and Engineering > School of Engineering > Biomedical Engineering
Journal Name:Analyst
Publisher:Royal Society of Chemistry
ISSN:0003-2654
ISSN (Online):1364-5528
Published Online:13 December 2017
Copyright Holders:Copyright © 2017 Royal Society of Chemistry
First Published:First published in Analyst 143(4):843-849
Publisher Policy:Reproduced under a Creative Commons License

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