Rambach, R. W., Biswas, P., Yadav, A., Garstecki, P. and Franke, T. (2018) Fast selective trapping and release of picoliter droplets in a 3D microfluidic PDMS multi-trap system with bubbles. Analyst, 143(4), pp. 843-849. (doi: 10.1039/c7an01100h) (PMID:29234760)
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Abstract
The selective manipulation and incubation of individual picoliter drops in high-throughput droplet based microfluidic devices still remains challenging. We used a surface acoustic wave (SAW) to induce a bubble in a 3D designed multi-trap polydimethylsiloxane (PDMS) device to manipulate multiple droplets and demonstrate the selection, incubation and on-demand release of aqueous droplets from a continuous oil flow. By controlling the position of the acoustic actuation, individual droplets are addressed and selectively released from a droplet stream of 460 drops per s. A complete trapping and releasing cycle can be as short as 70 ms and has no upper limit for incubation time. We characterize the fluidic function of the hybrid device in terms of electric power, pulse duration and acoustic path.
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Biswas, Ms Preetika and Franke, Professor Thomas |
Authors: | Rambach, R. W., Biswas, P., Yadav, A., Garstecki, P., and Franke, T. |
College/School: | College of Science and Engineering > School of Engineering > Biomedical Engineering |
Journal Name: | Analyst |
Publisher: | Royal Society of Chemistry |
ISSN: | 0003-2654 |
ISSN (Online): | 1364-5528 |
Published Online: | 13 December 2017 |
Copyright Holders: | Copyright © 2017 Royal Society of Chemistry |
First Published: | First published in Analyst 143(4):843-849 |
Publisher Policy: | Reproduced under a Creative Commons License |
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