Method and device for confocal Raman spectrum detection with high spatial discrimination

Beijing Institute of Technology (2014) Method and device for confocal Raman spectrum detection with high spatial discrimination. .

Abstract

The invention belongs to the technical field of optical microscopic imaging and spectral measurement, and relates to a method and a device for confocal Raman spectrum detection with high spatial discrimination. According to the method and the device, confocal technique is integrated into the spectrum detection; nondestructive separation is carried out on Rayleigh scattering light and Raman scattering light by using of a dichroic beam splitting system (13); by using the characteristic that the maximum value of a confocal curve (34) corresponds to a focal position accurately, spectral information exciting a light spot focal position is accurately acquired through maximizing; and the spectrum detection with the high spatial discrimination is achieved, and the method and the device which are capable of achieving the sample microcell spectrum detection with the high spatial discrimination are formed. The method and the device for the confocal Raman spectrum detection with the high spatial discrimination have the advantages of being accurate in positioning, high in spatial discrimination, high in spectrum detection sensitivity and the like, and has broad application prospect in the fields of biomedicine, court evidence collection and the like.

• Item Type: Patents
• Additional Information: Publication Number: CN103105231A.
• Status: Published
• Glasgow Author(s) Enlighten ID: Cui, Dr Han
• Authors: Zhao, W., Cui, H., Qiu, L., and Wang, Y.
• Subjects: Q Science > QC Physics
• College/School: College of Science and Engineering > School of Engineering > Biomedical Engineering
• First Published: 15 October 2014