Laser Differential Confocal Mapping-Spectrum Microscopic Imaging Method and Device

Beijing Institute of Technology (2016) Laser Differential Confocal Mapping-Spectrum Microscopic Imaging Method and Device. .

Beijing Institute of Technology (2016) Laser Differential Confocal Mapping-Spectrum Microscopic Imaging Method and Device. .

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Publisher's URL: https://patents.google.com/patent/US9410880B2/en

Abstract

The present invention belongs to a technical field of optical microscopic imaging and spectral measurement, and discloses a laser differential confocal mapping-spectrum microscopic imaging method and device. The core concept of the present invention is to combine the differential confocal detection and the spectrum detection techniques and use a dichroic beam splitting system (13) to separate the Rayleigh light for geometric position detection from the Raman scattering light for spectrum detection, by mean of the property that the zero-cross point of the differential confocal curve (43) accurately corresponds to the focus of the objective, the spectral information at focus of the excitation spot being accurately captured by the zero trigger to accomplish the spectrum detection with high spatial resolution. Therefore, the present invention provides a method and device that may be able to accomplish the spectrum detection with high spatial resolution to a micro-area of a sample.

Item Type:Patents
Additional Information:Publication Number: US9410880B2.
Status:Published
Glasgow Author(s) Enlighten ID:Cui, Dr Han
Authors: Zhao, W., Cui, H., Qiu, L., and Wang, Y.
Subjects:Q Science > QC Physics
College/School:College of Science and Engineering > School of Engineering > Biomedical Engineering
First Published:09 August 2016

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