Asociación entre diabetes mellitus tipo 2 y actividad física en personas con antecedentes familiares de diabetes = Association between type 2 diabetes and physical activity in individuals with family history of diabetes

Petermann, F., Díaz-Martínez, X., Garrido-Méndez, Á., Leiva, A. M., Martínez, M. A., Salas, C., Poblete-Valderrama, F. and Celis-Morales, C. (2018) Asociación entre diabetes mellitus tipo 2 y actividad física en personas con antecedentes familiares de diabetes = Association between type 2 diabetes and physical activity in individuals with family history of diabetes. Gaceta Sanitaria, 32(3), pp. 230-235. (doi: 10.1016/j.gaceta.2017.09.008) (PMID:29203323)

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Abstract

Objetivo: Investigar si la asociación entre diabetes mellitus tipo 2 (DMT2) y antecedentes familiares de DMT2 resulta modificada por los niveles de actividad física en población chilena. Método: Se incluyeron en el estudio 5129 participantes de la Encuesta Nacional de Salud de Chile. El tiempo destinado a realizar actividad física se determinó por el cuestionario GPAQ v2, y los antecedentes familiares mediante el autorreporte de cada participante. La asociación entre DMT2, antecedentes familiares de DMT2 y actividad física fue investigada por sexo mediante regresión logística. Resultados: El riesgo de desarrollar DMT2 en personas con antecedentes familiares de esta enfermedad es elevado, independientemente de su nivel de actividad física y de su adiposidad. Tanto las mujeres como los hombres físicamente inactivos y con antecedentes familiares de DMT2 presentan mayor probabilidad de desarrollar DMT2 (odds ratio [OR] mujeres: 5,49; intervalo de confianza del 95% [IC95%]: 3,85-7,84; p <0,0001; y OR hombres: 8,16; IC95%: 4,96-13,4; p <0,0001), comparados con sus pares sin antecedentes familiares y activos físicamente. Conclusión: Dado el alto riesgo de desarrollar DMT2 que presentan los individuos con antecedentes familiares de esta enfermedad, y el efecto de la actividad física en la disminución de dicho riesgo, es esencial incrementar los niveles de actividad física en la población que presenta mayor susceptibilidad a DMT2. <br/> <br/> Objective: To investigate whether the association between type 2 diabetes (T2D) and family history of diabetes is modified by the levels of physical activity in the Chilean population. Method: In this study were included 5129 participants from the cross-sectional 2009-2010 National Health Survey. Physical activity level was assessed using the Global Physical Activity Questionnaire and family history of T2D, through self-reporting. The association between diabetes, family history of diabetes and physical activity was determined using logistic regression. Results: The odds of developing T2D in people with family history of this pathology is high, independent of their levels of physical activity and adiposity. Both men and women with family history of T2D have a higher probability of developing T2D. The odds ratio for having T2D was 5,49 (95%CI: 3,85-7,84; p <0,0001) in women, and 8,16 (95%CI: 4,96-13,4; p <0,0001) in men with family history of T2D and low levels of physical activity in comparison to those with high levels of physical activity and without a family history. Conclusion: Given the elevated risk of developing T2D presented by individuals with a family history of this pathology, and the effect of physical activity in reducing such risk, people with family history of diabetes may need higher levels of physical activity to attenuate their susceptibility to T2D.

Item Type:Articles
Keywords:Actividad física, Adiposidad, Adiposity, Diabetes mellitus tipo 2, Ejercicio, Exercise, Obesidad, Obesity, Physical activity, Type 2 diabetes
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Celis, Dr Carlos and Petermann, Mrs Fanny
Authors: Petermann, F., Díaz-Martínez, X., Garrido-Méndez, Á., Leiva, A. M., Martínez, M. A., Salas, C., Poblete-Valderrama, F., and Celis-Morales, C.
College/School:College of Medical Veterinary and Life Sciences > Institute of Cardiovascular and Medical Sciences
Journal Name:Gaceta Sanitaria
Publisher:Elsevier Espana
ISSN:0213-9111
ISSN (Online):1578-1283
Published Online:06 December 2017
Copyright Holders:Copyright © 2017 SESPAS
First Published:First published in Gaceta Sanitaria 32(3): 230-235
Publisher Policy:Reproduced under a Creative Commons License

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