Ca2+ leak, what is it? Why should we care? Can it be managed?

Boyden, P. A. and Smith, G. L. (2018) Ca2+ leak, what is it? Why should we care? Can it be managed? Heart Rhythm, 15(4), pp. 607-614. (doi:10.1016/j.hrthm.2017.11.018) (PMID:29157722)

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Abstract

For arrhythmia triggers that are secondary to dysfunctional intracellular Ca2+ cycling, there are few if any specific agents that target exactly the Ca2+ handling machinery. However, in the literature to date, several candidates have been proposed. We review here these agents with the idea that in the future these agents or those derived thereof will prove invaluable in clinical application.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Smith, Professor Godfrey
Authors: Boyden, P. A., and Smith, G. L.
College/School:College of Medical Veterinary and Life Sciences > Institute of Cardiovascular and Medical Sciences
Journal Name:Heart Rhythm
Publisher:Elsevier
ISSN:1547-5271
ISSN (Online):1556-3871
Published Online:20 November 2017
Copyright Holders:Copyright © 2017 Heart Rhythm Society
First Published:First published in Heart Rhythm 15(4): 607-614
Publisher Policy:Reproduced in accordance with the publisher copyright policy

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