Spontaneous models of Guillain-Barré syndrome in animals

Rupp, A. F. (2016) Spontaneous models of Guillain-Barré syndrome in animals. In: Willison, H. J. and Goodfellow, J. A. (eds.) GBS100: Celebrating a Century of Progress in Guillain-Barré Syndrome. Peripheral Nerve Society: San Diego, CA, pp. 379-388. ISBN 9780997510300

Abstract

Spontaneous conditions similar to those of Guillain-Barré syndrome (GBS), leading to acute ascending paralysis and associated with polyradiculoneuropathies of unknown origin, have been reported in a number of different animal species. Unfortunately, in many cases, comparison and interpretation of these reports is challenging, since depending on when these examinations were conducted and whether the animals survived, the extent and modality of investigations carried out often varies. The majority of descriptions focus on dogs, cats and chickens. Individual case reports include the description of a chimpanzee with acute onset of ascending, symmetrical, monophasic flaccid paralysis and high protein in the CSF, possibly associated with a preceding rabies vaccination [1], and polyradiculoneuritis with mononuclear cell infiltrates, demyelination and Schwann cell proliferation in a 6-week-old goat [2].

• Item Type: Book Sections
• Status: Published
• Glasgow Author(s) Enlighten ID: Rupp, Dr Angie
• Authors: Rupp, A. F.
• College/School: College of Medical Veterinary and Life Sciences > School of Biodiversity, One Health & Veterinary Medicine
• Publisher: Peripheral Nerve Society
• ISBN: 9780997510300

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