Human immunodeficiency virus. Phylogeny and the origin of HIV-1

Rambaut, A., Robertson, D.L. , Pybus, O.G., Peeters, M. and Holmes, E.C. (2001) Human immunodeficiency virus. Phylogeny and the origin of HIV-1. Nature, 410(6832), pp. 1047-1048. (doi:10.1038/35074179) (PMID:11323659)

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Abstract

The origin of human immunodeficiency virus type 1 (HIV-1) is controversial. We show here that viruses obtained from the Democratic Republic of Congo in Africa have a quantitatively different phylogenetic tree structure from those sampled in other parts of the world. This indicates that the structure of HIV-1 phylogenies is the result of epidemiological processes acting within human populations alone, and is not due to multiple cross-species transmission initiated by oral polio vaccination.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Robertson, Professor David
Authors: Rambaut, A., Robertson, D.L., Pybus, O.G., Peeters, M., and Holmes, E.C.
College/School:College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
Journal Name:Nature
Publisher:Nature Publishing Group
ISSN:0028-0836
ISSN (Online):1476-4687

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