Evidence of recombination between divergent hepatitis E viruses

van Cuyck, H., Fan, J., Robertson, D. L. and Roques, P. (2005) Evidence of recombination between divergent hepatitis E viruses. Journal of Virology, 79(14), pp. 9306-9314. (doi:10.1128/JVI.79.14.9306-9314.2005) (PMID:15994825) (PMCID:PMC1168788)

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Abstract

Phylogenetic and recombination analysis was performed on 32 complete hepatitis E virus (HEV) genomes from infected humans and pigs. For the first time, evidence for recombination between divergent HEV strains was obtained, with at least two strains being found to have discordant phylogenetic relationships consistent with the occurrence of intragenotype recombination. This finding confirms that humans can be dually infected with divergent HEV strains and has implications for the emergence and evolution of new HEV epidemics.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Robertson, Professor David
Authors: van Cuyck, H., Fan, J., Robertson, D. L., and Roques, P.
College/School:College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
Journal Name:Journal of Virology
Publisher:American Society for Microbiology
ISSN:0022-538X
ISSN (Online):1098-5514

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