SYSTEMS-2: a randomised phase II study of radiotherapy dose escalation for pain control in malignant pleural mesothelioma

Ashton, M. et al. (2018) SYSTEMS-2: a randomised phase II study of radiotherapy dose escalation for pain control in malignant pleural mesothelioma. Clinical and Translational Radiation Oncology, 8, pp. 45-49. (doi:10.1016/j.ctro.2017.11.004)

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Abstract

SYSTEMS-2 is a randomised study of radiotherapy dose escalation for pain control in 112 patients with malignant pleural mesothelioma (MPM). Standard palliative (20Gy/5#) or dose escalated treatment (36Gy/6#) will be delivered using advanced radiotherapy techniques and pain responses will be compared at week 5. Data will guide optimal palliative radiotherapy in MPM.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Ashton, Dr Miranda and Kelly, Mrs Caroline and Stobo, Mr Jon and Chalmers, Professor Anthony
Authors: Ashton, M., O'Rourke, N., Macleod, N., Laird, B., Stobo, J., Kelly, C., Alexander, L., Franks, K., Moore, K., Currie, S., Valentine, R., and Chalmers, A.J.
College/School:College of Medical Veterinary and Life Sciences > Institute of Cancer Sciences
Journal Name:Clinical and Translational Radiation Oncology
Publisher:Elsevier
ISSN:2405-6308
ISSN (Online):2405-6308
Published Online:21 November 2017
Copyright Holders:Copyright © 2017 The Authors
First Published:First published in Clinical and Translational Radiation Oncology 2017
Publisher Policy:Reproduced under a Creative Commons License

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