Synthesis of bicyclic tripeptides inspired by the ABC-ring system of vancomycin through ruthenium-based cyclization chemistries

Yang, X., Beroske, L. P., Kemmink, J., Rijkers, D. T.S. and Liskamp, R. M.J. (2017) Synthesis of bicyclic tripeptides inspired by the ABC-ring system of vancomycin through ruthenium-based cyclization chemistries. Tetrahedron Letters, 58(48), pp. 4542-4546. (doi:10.1016/j.tetlet.2017.10.046)

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Abstract

The synthesis of a bicyclic tripeptide that mimics the ABC ring system of vancomycin is described by using a ring closing metathesis (RCM) – peptide coupling – ruthenium-catalyzed azide-alkyne cycloaddition (RuAAC) strategy.

Item Type:Articles
Additional Information:This research was supported by the China Scholarship Council (CSC) awarded to X.Y
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Liskamp, Professor Robert
Authors: Yang, X., Beroske, L. P., Kemmink, J., Rijkers, D. T.S., and Liskamp, R. M.J.
College/School:College of Science and Engineering > School of Chemistry
Journal Name:Tetrahedron Letters
Publisher:Elsevier
ISSN:0040-4039
ISSN (Online):1873-3581
Published Online:19 October 2017
First Published:First published in Tetrahedron Letters 58(48):4542-4546
Publisher Policy:Reproduced under a Creative Commons License

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