Characterizing cardiac involvement in chronic kidney disease using CMR—a systematic review

Mangion, K., McDowell, K., Mark, P. B. and Rutherford, E. (2018) Characterizing cardiac involvement in chronic kidney disease using CMR—a systematic review. Current Cardiovascular Imaging Reports, 11, 2. (doi:10.1007/s12410-018-9441-9) (PMID:29497467) (PMCID:PMC5818546)

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Abstract

Purpose of Review: The aim of the review was to identify and describe recent advances (over the last 3 years) in cardiac magnetic resonance (CMR) imaging in patients with chronic kidney disease (CKD). We conducted a literature review in line with current guidelines. Recent Findings: The authors identified 22 studies. Patients with CKD had left ventricular global and regional dysfunction and adverse remodeling. Stress testing with CMR revealed a reduced stress-response in CKD patients. Native T1 relaxation times (as a surrogate markers of fibrosis) are elevated in CKD patients, proportional to disease duration. Patients with CKD have reduced strain magnitudes and reduced aortic distensibility. Summary: CMR has diagnostic utility to identify and characterize cardiac involvement in this patient group. A number of papers have described novel findings over the last 3 years, suggesting that CMR has potential to become more widely used in studies in this patient group.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Rutherford, Dr Elaine and Mangion, Dr Kenneth and Mark, Dr Patrick
Authors: Mangion, K., McDowell, K., Mark, P. B., and Rutherford, E.
College/School:College of Medical Veterinary and Life Sciences > Institute of Cardiovascular and Medical Sciences
Journal Name:Current Cardiovascular Imaging Reports
Publisher:Springer
ISSN:1941-9066
ISSN (Online):1941-9074
Published Online:31 January 2018
Copyright Holders:Copyright © 2018 The Authors
First Published:First published in Current Cardiovascular Imaging Reports 11:2
Publisher Policy:Reproduced under a Creative Commons License

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
699321Myocardial strain measurements in survivors of acute ST-elevation myocardial infarction: implementation and prognostic significance of novel magnetic resonance imaging methods.Colin BerryBritish Heart Foundation (BHF)FS/15/54/31639RI CARDIOVASCULAR & MEDICAL SCIENCES
765281Endowment Fellowship Funding for Project Ref: GN16ON418Kenneth MangionNHS Greater Glasgow and Clyde Endowment Funds (NHSGGCEN)GN16ON418RI CARDIOVASCULAR & MEDICAL SCIENCES