So far, yet so close: α-Catenin dimers help migrating cells get together

Machesky, L. and Braga, V. M.M. (2017) So far, yet so close: α-Catenin dimers help migrating cells get together. Journal of Cell Biology, 216(11), pp. 3437-3439. (doi:10.1083/jcb.201709056) (PMID:29051263)

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Abstract

Epithelial cells in tissues use their actin cytoskeletons to stick together, whereas unattached cells make active plasma membrane protrusions to migrate. In this issue, Wood et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201612006) show that the junction component α-catenin is critical in freely moving cells to promote adhesion and migration.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Machesky, Professor Laura
Authors: Machesky, L., and Braga, V. M.M.
College/School:College of Medical Veterinary and Life Sciences > Institute of Cancer Sciences
Journal Name:Journal of Cell Biology
Publisher:Rockefeller University Press
ISSN:0021-9525
ISSN (Online):1540-8140
Published Online:19 October 2017
Copyright Holders:Copyright © 2017 Machesky and Braga
First Published:First published in Journal of Cell Biology 216(11):3437-3439
Publisher Policy:Reproduced under a Creative Commons License

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