The role of corruption and unethical behaviour in precluding the placement of industry sponsored clinical trials in sub-Saharan Africa: stakeholder views

Egharevba, E. and Atkinson, J. (2016) The role of corruption and unethical behaviour in precluding the placement of industry sponsored clinical trials in sub-Saharan Africa: stakeholder views. Contemporary Clinical Trials Communications, 3, pp. 102-110. (doi: 10.1016/j.conctc.2016.04.009)

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Abstract

Clinical trials still represent the gold standard in testing the safety and efficacy of new and existing treatments. However, developing regions including sub-Saharan Africa remain underrepresented in pharmaceutical industry sponsored trials for a number of reasons including fear of corruption and unethical behaviour. This fear exists both on the part of pharmaceutical companies, and investigators carrying out research in the region. The objective of this research was to understand the ethical considerations associated with the conduct of pharmaceutical industry sponsored clinical trials in sub-Saharan Africa. Corruption was identified as a significant issue by a number of stakeholders who participated in semi-structured interviews and completed questionnaires. Additionally, fear of being perceived as corrupt or unethical even when conducting ethically sound research was raised as a concern. Thus corruption, whether actual or perceived, is one of a number of issues which have precluded the placement of a greater number of pharmaceutical sponsored clinical trials in this region. More discussion around corruption with all relevant stakeholders is required in order for progress to be made and to enable greater involvement of sub-Saharan African countries in the conduct of industry sponsored clinical trials.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Atkinson, Professor Jacqueline and Egharevba, Terry
Authors: Egharevba, E., and Atkinson, J.
College/School:College of Medical Veterinary and Life Sciences > Institute of Health and Wellbeing > Public Health
Journal Name:Contemporary Clinical Trials Communications
Publisher:Elsevier
ISSN:2451-8654
ISSN (Online):2451-8654
Published Online:30 April 2016
Copyright Holders:Copyright © 2016 The Authors
First Published:First published in Contemporary Clinical Trials Communications 3:102-110
Publisher Policy:Reproduced under a Creative Commons License

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