Effects of changes to the stable environment on the exhalation of ethane, carbon monoxide and hydrogen peroxide by horses with respiratory inflammation

Wyse, C.A. et al. (2005) Effects of changes to the stable environment on the exhalation of ethane, carbon monoxide and hydrogen peroxide by horses with respiratory inflammation. Veterinary Record, 157(14), pp. 408-412. (doi:10.1136/vr.157.14.408)

Wyse, C.A. et al. (2005) Effects of changes to the stable environment on the exhalation of ethane, carbon monoxide and hydrogen peroxide by horses with respiratory inflammation. Veterinary Record, 157(14), pp. 408-412. (doi:10.1136/vr.157.14.408)

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Abstract

The aim of this study was to assess the effects of changes to the stable environment on exhaled markers of respiratory inflammation in six horses with clinical histories of recurrent airway obstruction. The horses were maintained for two weeks under conventional stable management (straw bedding and hay) and for two weeks on a reduced-dust regimen (paper bedding and ensiled grass), in a crossover study design. Exhaled ethane and carbon monoxide (CO) and exhaled breath condensate hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>) were measured every three days under each regimen. The presence of clinical signs of airway inflammation (nasal discharge and cough) was monitored daily. The reduced-dust regimen was associated with fewer clinical signs of airway inflammation than the conventional regimen. Exhaled ethane and CO were significantly lower on the reduced-dust regimen and these markers were correlated with clinical signs of respiratory inflammation, but exhaled H<sub>2</sub>O<sub>2</sub> was not affected by the management regimen.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Wyse, Dr Cathy and Preston, Professor Thomas and Love, Professor Sandy and Padgett, Professor Miles and Cumming, Professor David and Hotchkiss, Dr Joel and Cooper, Professor Jonathan and Yam, Dr Philippa
Authors: Wyse, C.A., Skeldon, K., Hotchkiss, J.W., Gibson, G., Yam, P.S., Christley, R.M., Preston, T., Cumming, D.R.S., Padgett, M., Cooper, J.C., and Love, S.
College/School:College of Medical Veterinary and Life Sciences > Institute of Biodiversity Animal Health and Comparative Medicine
College of Science and Engineering > School of Engineering > Biomedical Engineering
College of Science and Engineering > School of Engineering > Electronics and Nanoscale Engineering
College of Science and Engineering > Scottish Universities Environmental Research Centre
College of Medical Veterinary and Life Sciences > School of Veterinary Medicine
Journal Name:Veterinary Record
Publisher:B M J Group
ISSN:0042-4900
ISSN (Online):2042-7670

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