Continuous flow separation of particles within an asymmetric microfluidic device

Zhang, X., Cooper, J. M. , Monaghan, P. B. and Haswell, S. J. (2006) Continuous flow separation of particles within an asymmetric microfluidic device. Lab on a Chip, 6, pp. 561-566. (doi:10.1039/b515272k)

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Abstract

A microfluidic based device has been developed for the continuous separation of polymer microspheres, taking advantage of the flow characteristics of systems. The chip consists of an asymmetric cavity with variable channel width which enables continuous amplification of the particle separation for different size particles within the laminar flow profile. The process has been examined by varying the sample inlet position, the sample to media flow rate ratio, and the total flow rate. This technique can be applied for manipulating both microscale biological and colloidal particles within microfluidic systems.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Monaghan, Dr Paul and Haswell, Prof Stephen and Cooper, Professor Jonathan
Authors: Zhang, X., Cooper, J. M., Monaghan, P. B., and Haswell, S. J.
College/School:College of Science and Engineering > School of Engineering > Biomedical Engineering
College of Science and Engineering > School of Engineering > Electronics and Nanoscale Engineering
Journal Name:Lab on a Chip
Publisher:Royal Society of Chemistry
ISSN:1473-0197
ISSN (Online):1473-0189
Published Online:13 March 2006

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