Hypothalamic neuropeptide Y mRNA is increased after feed restriction in growing broilers

Boswell, T., Dunn, I. C. and Corr, S. A. (1999) Hypothalamic neuropeptide Y mRNA is increased after feed restriction in growing broilers. Poultry Science, 78(8), pp. 1203-1207. (doi:10.1093/ps/78.8.1203) (PMID:10472848)

Boswell, T., Dunn, I. C. and Corr, S. A. (1999) Hypothalamic neuropeptide Y mRNA is increased after feed restriction in growing broilers. Poultry Science, 78(8), pp. 1203-1207. (doi:10.1093/ps/78.8.1203) (PMID:10472848)

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Abstract

As part of an approach to uncover the brain mechanisms underlying the regulation of energy balance in broiler chickens, we investigated the possible role of neuropeptide Y (NPY). The NPY gene expression was measured in the hypothalamus of birds from a standard Ross male line and a Ross relaxed line. Both lines are derived from the same founder stock, but the relaxed line has not been selected for rapid growth since 1976. Birds of each line consumed feed either ad libitum or according to a standard commercial restricted feeding program. All groups of birds were killed at an average body weight of 2.4 kg. The NPY mRNA levels were significantly increased (P <0.0001) in feed-restricted birds of both lines relative to ad libitum controls. No significant differences were detected between the lines. These results show that NPY gene expression in the broiler hypothalamus is sensitive to changes in energetic status, as it is in mammals. However, the maintenance of selection pressure for high growth rate is not associated with altered hypothalamic NPY mRNA levels in the ad libitum or restricted state.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Corr, Sandra
Authors: Boswell, T., Dunn, I. C., and Corr, S. A.
College/School:College of Medical Veterinary and Life Sciences > School of Veterinary Medicine
Journal Name:Poultry Science
Publisher:Oxford University Press
ISSN:0032-5791
ISSN (Online):1525-3171

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