Trial-by-trial co-variation of pre-stimulus EEG alpha power and visuospatial bias reflects a mixture of stochastic and deterministic effects

Benwell, C. S.Y., Keitel, C. , Harvey, M. , Gross, J. and Thut, G. (2018) Trial-by-trial co-variation of pre-stimulus EEG alpha power and visuospatial bias reflects a mixture of stochastic and deterministic effects. European Journal of Neuroscience, 48(7), pp. 2566-2584. (doi:10.1111/ejn.13688) (PMID:28887893)

[img]
Preview
Text
146653.pdf - Published Version
Available under License Creative Commons Attribution.

2MB

Abstract

Human perception of perithreshold stimuli critically depends on oscillatory EEG-activity prior to stimulus-onset. However, it remains unclear exactly which aspects of perception are shaped by this pre-stimulus activity and what role stochastic (trial-by-trial) variability plays in driving these relationships. We employed a novel Jackknife approach to link single-trial variability in oscillatory activity to psychometric measures from a task that requires judgement of the relative length of two line-segments (the landmark task). The results provide evidence that pre-stimulus alpha fluctuations influence perceptual bias. Importantly, a mediation analysis showed that this relationship is partially driven by long-term (deterministic) alpha-changes over time, highlighting the need to account for sources of trial-by-trial variability when interpreting EEG predictors of perception. These results provide fundamental insight into the nature of the effects of ongoing oscillatory activity on perception. The jackknife approach we implemented may serve to identify and investigate neural signatures of perceptual relevance in more detail.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Thut, Professor Gregor and Keitel, Dr Christian and Harvey, Dr Monika and Gross, Professor Joachim and Benwell, Mr Christopher
Authors: Benwell, C. S.Y., Keitel, C., Harvey, M., Gross, J., and Thut, G.
College/School:College of Medical Veterinary and Life Sciences > Institute of Neuroscience and Psychology
College of Science and Engineering > School of Psychology
Journal Name:European Journal of Neuroscience
Publisher:Wiley
ISSN:0953-816X
ISSN (Online):1460-9568
Published Online:09 September 2017
Copyright Holders:Copyright © 2017 The Authors
First Published:First published in European Journal of Neuroscience 48(7):2566-2584
Publisher Policy:Reproduced under a Creative Commons License

University Staff: Request a correction | Enlighten Editors: Update this record

Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
597911Natural and modulated neural communication: State-dependent decoding and driving of human Brain OscillationsGregor ThutWellcome Trust (WELLCOTR)098434/Z/12/ZINP - CENTRE FOR COGNITIVE NEUROIMAGING
597051Natural and modulated neural communication: State-dependent decoding and driving of human Brain Oscillations.Joachim GrossWellcome Trust (WELLCOTR)098433/Z/12/ZINP - CENTRE FOR COGNITIVE NEUROIMAGING