Wall, G. R., Perinpanathan, D. and Clark, D. A. (2012) Comparison of the QIAGEN artus HIV-1 QS-RGQ test with the Roche COBAS AmpliPrep/COBAS TaqMan HIV-1 test v2.0. Journal of Clinical Virology, 55(1), pp. 62-66. (doi: 10.1016/j.jcv.2012.05.014) (PMID:22739101)
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Abstract
Background: Regular HIV-1 viral load monitoring is standard of care in the developed world for patients infected with HIV-1. Objectives: Here we report a comparative evaluation of the established Roche COBAS AmpliPrep/COBAS TaqMan HIV-1 v2.0 test (Roche Diagnostics Ltd, Burgess Hill, UK) and the new artus HIV-1 QS-RGQ test (QIAGEN Ltd, Crawley, UK). Study design: 169 clinical EDTA-plasma samples were tested, all of known HIV-1 subtype. Results: The mean overall log10 c/ml difference was 0.10 (QIAGEN – Roche). Conclusion: The artus HIV-1 QS-RGQ test compared well with the Roche TaqMan HIV-1 v2.0 test, and Bland–Altman analysis showed good agreement between the two systems across a wide range of subtypes.
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Clark, Dr Duncan |
Authors: | Wall, G. R., Perinpanathan, D., and Clark, D. A. |
College/School: | College of Medical Veterinary and Life Sciences |
Journal Name: | Journal of Clinical Virology |
Publisher: | Elsevier |
ISSN: | 1386-6532 |
ISSN (Online): | 1873-5967 |
Published Online: | 27 June 2012 |
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