Chignola, R., Sega, M., Stella, S., Vyshemirsky, V. and Milotti, E. (2016) From single-cell dynamics to scaling laws in oncology. In: Gerstman, B. S. (ed.) Research on the Physics of Cancer. World Scientific: Singapore ; New Jersey, pp. 97-108. ISBN 9789814730259 (doi: 10.1142/9789814730266_0006)
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Abstract
We are developing a biophysical model of tumor biology. We follow a strictly quantitative approach where each step of model development is validated by comparing simulation outputs with experimental data. While this strategy may slow down our advancements, at the same time it provides an invaluable reward: we can trust simulation outputs and use the model to explore territories of cancer biology where current experimental techniques fail. Here, we review our multi-scale biophysical modeling approach and show how a description of cancer at the cellular level has led us to general laws obeyed by both in vitro and in vivo tumors. Read More: http://www.worldscientific.com/doi/abs/10.1142/9789814730266_0006
| Item Type: | Book Sections |
|---|---|
| Status: | Published |
| Glasgow Author(s) Enlighten ID: | Vyshemirsky, Dr Vladislav |
| Authors: | Chignola, R., Sega, M., Stella, S., Vyshemirsky, V., and Milotti, E. |
| College/School: | College of Science and Engineering > School of Mathematics and Statistics > Statistics |
| Journal Name: | Research on the Physics of Cancer |
| Publisher: | World Scientific |
| ISBN: | 9789814730259 |
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