Renal neuroendocrine control of desiccation and cold tolerance by Drosophila suzukii

Terhzaz, S. , Alford, L., Yeoh, J. G.C. , Marley, R., Dornan, A. J. , Dow, J. A.T. and Davies, S. A. (2018) Renal neuroendocrine control of desiccation and cold tolerance by Drosophila suzukii. Pest Management Science, 74(4), pp. 800-810. (doi:10.1002/ps.4663) (PMID:28714258) (PMCID:PMC5888198)

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Abstract

Background: Neuropeptides are central to the regulation of physiological, and behavioural processes in insects, directly impacting cold and desiccation survival. However, little is known about the control mechanisms governing these responses in D. suzukii. The close phylogenetic relationship of D. suzukii with D. melanogaster allows, through genomic and functional studies, an insight into the mechanisms directing stress tolerance in D. suzukii. Results: Capa, Leucokinin, DH44 and DH31 neuropeptides demonstrate a high level of conservation between D. suzukii and D. melanogaster with respect to peptide sequences, neuronal expression, receptor localisation, and diuretic function in the Malpighian tubules. Despite D. suzukii’s ability to populate cold environments, they proved sensitive to both cold and desiccation. Furthermore, in D. suzukii, Capa acts as a desiccation-and cold stress-responsive gene, while DH44 gene expression is increased only after desiccation exposure, and the LK gene after nonlethal cold stress recovery. Conclusion: This study provides a comparative investigation into stress tolerance mediation by neuroendocrine signalling in two Drosophila species, providing evidence that similar signalling pathways control fluid secretion in the Malpighian tubules. Identifying processes governing specific environmental stresses affecting D. suzukii could lead to the development of targeted integrated management strategies to control insect pest populations.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Alford, Dr Lucy and Dow, Professor Julian and Terhzaz, Dr Selim and Davies, Professor Shireen and Dornan, Dr Anthony and Marley, Dr Richard and Yeoh, Dr Joseph
Authors: Terhzaz, S., Alford, L., Yeoh, J. G.C., Marley, R., Dornan, A. J., Dow, J. A.T., and Davies, S. A.
College/School:College of Medical Veterinary and Life Sciences > Institute of Molecular Cell and Systems Biology
Journal Name:Pest Management Science
Publisher:Wiley
ISSN:1526-498X
ISSN (Online):1526-4998
Published Online:17 July 2017
Copyright Holders:Copyright © 2017 Society of Chemical Industry
First Published:First published in Pest Management Science 74(4):800-810
Publisher Policy:Reproduced under a Creative Commons License

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
664541nEUROSTRESSPEPShireen DaviesEuropean Commission (EC)634361RI MOLECULAR CELL & SYSTEMS BIOLOGY
737981Functional analysis of insect neuropeptide G protein-coupled receptorsShireen DaviesBiotechnology and Biological Sciences Research Council (BBSRC)BB/P008097/1RI MOLECULAR CELL & SYSTEMS BIOLOGY