Flexible synthesis of polyfunctionalised 3-fluoropyrroles

Cogswell, T. J., Donald, C. S. and Marquez, R. (2016) Flexible synthesis of polyfunctionalised 3-fluoropyrroles. Organic and Biomolecular Chemistry, 14(1), pp. 183-190. (doi: 10.1039/c5ob02155c) (PMID:26555030)

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An efficient and selective approach for the synthesis of polyfunctionalised 3-fluoropyrroles has been developed starting from commercial aldehydes. The methodology is concise, efficient and allows for the modular and systematic assembly of polysubstituted 3-fluoropyrroles. This synthesis provides an alternative and highly convergent strategy for the generation of these chemically and biologically important units.

Item Type:Articles
Glasgow Author(s) Enlighten ID:Cogswell, Mr Thomas
Authors: Cogswell, T. J., Donald, C. S., and Marquez, R.
College/School:College of Science and Engineering > School of Chemistry
Journal Name:Organic and Biomolecular Chemistry
Publisher:Royal Society of Chemistry
ISSN (Online):1477-0539
Published Online:05 November 2015
Copyright Holders:Copyright © 2016 The Royal Society of Chemistry
First Published:First published in Organic and Biomolecular Chemistry 14(1):183-190
Publisher Policy:Reproduced under a Creative Commons License

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
504321New Chemistry Approaches for the Next Generation of HealthcareRudi MarquezEngineering and Physical Sciences Research Council (EPSRC)EP/H005692/1CHEM - CHEMISTRY