Lgr5 joins the club of gastric stem cell markers in the corpus

Phesse, T. J. and Sansom, O. J. (2017) Lgr5 joins the club of gastric stem cell markers in the corpus. Nature Cell Biology, 19(7), pp. 752-754. (doi:10.1038/ncb3567) (PMID:28659641)

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Abstract

Several markers of gastric stem cells have been identified in recent years. Now a study demonstrates that Lgr5 marks a population of reserve stem cells located at the base of the corpus glands of the gastric epithelium, and that these cells can also act as a cell-of-origin for gastric tumorigenesis.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Sansom, Professor Owen
Authors: Phesse, T. J., and Sansom, O. J.
College/School:College of Medical Veterinary and Life Sciences > Institute of Cancer Sciences
Journal Name:Nature Cell Biology
Publisher:Nature Publishing Group
ISSN:1465-7392
ISSN (Online):1476-4679
Published Online:29 June 2017

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