Klaus, V. and Clark, J. S. (2017) Thioether-catalysed tandem synthesis of furans and cyclic ethers or lactones. Synlett, 28(11), pp. 1358-1362. (doi: 10.1055/s-0036-1588758)
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Abstract
Acyclic conjugated ynenediones tethered to an alcohol or carboxylic acid are converted into furanyl-substituted cyclic ethers or lactones in a single step by treatment with the tetrahydrothiophene. Modest levels of diastereocontrol can be achieved in some cases where the presence of a substituent on the tether results in the creation of a second stereogenic centre upon formation of the cyclic ether or lactone.
| Item Type: | Articles (Letter) |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Klaus, Miss Verena and Clark, Professor Stephen |
| Authors: | Klaus, V., and Clark, J. S. |
| College/School: | College of Science and Engineering > School of Chemistry |
| Journal Name: | Synlett |
| Publisher: | Thieme Publishing |
| ISSN: | 0936-5214 |
| ISSN (Online): | 1437-2096 |
| Published Online: | 20 March 2017 |
| Copyright Holders: | Copyright © 2017 Georg Thieme Verlag |
| First Published: | First published in Synlett 28(11):1358-1362 |
| Publisher Policy: | Reproduced in accordance with the publisher copyright policy |
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