A G-rich sequence element common to Dictyostelium genes which differ radically in their patterns of expression

Ceccarelli, A., Mahbubani, H. J., Insall, R. , Schnitzler, G., Firtel, R. A. and Williams, J. G. (1992) A G-rich sequence element common to Dictyostelium genes which differ radically in their patterns of expression. Developmental Biology, 152(1), pp. 188-193. (doi:10.1016/0012-1606(92)90169-H) (PMID:1321061)

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Abstract

Removal of a G-rich element from the DIF-inducible, prestalk-, and stalk-specific ecmB gene reduces expression but cell-type specificity is retained. The ecmB element will functionally substitute for a homologous sequence upstream of CP2, a cAMP-inducible gene and is bound by GBF, the factor which interacts with the CP2 G box. These results suggest that the G box may play a similar stimulatory role in these two independently regulated genes where it presumably interacts with different ancillary promoter elements.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Insall, Professor Robert
Authors: Ceccarelli, A., Mahbubani, H. J., Insall, R., Schnitzler, G., Firtel, R. A., and Williams, J. G.
College/School:College of Medical Veterinary and Life Sciences > Institute of Cancer Sciences
Journal Name:Developmental Biology
Publisher:Elsevier
ISSN:0012-1606
ISSN (Online):1095-564X
Published Online:07 December 2004

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