Rycroft, D. S., Stirling, I. R. and Robins, D. J. (1992) Assignment of the 1H and 13C NMR spectra and conformational analysis of the pyrrolizidine alkaloid 13-O-acetyldicrotaline. Magnetic Resonance in Chemistry, 30(13), S42-S45. (doi: 10.1002/mrc.1260301310)
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Abstract
The <sup>1</sup>H and <sup>13</sup>C NMR spectra of the pyrrolizidine alkaloid 13-<i>O</i>-acetyldicrotaline were studied at 4.7 T. A full assignment of the <sup>1</sup>H and <sup>13</sup>C signals was achieved by application of a variety of NMR techniques, including homonuclear <sup>1</sup>H NOE difference, 2D <i>δ</i>H/<i>δ</i>H phase-sensitive COSY and <i>δ</i>C/<i>δ</i>H direct and long-range correlation experiments. The stereochemistry at C-13 in dicrotaline is confirmed to be <i>S</i>, and the conformation of the eleven-membered macrocycle is compared with that of related pyrrolizidine alkaloids.
Item Type: | Articles |
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Additional Information: | Invited contribution to special issue: Structure elucidation of natural products by NMR. |
Keywords: | Dicrotaline, eleven-membered ring, NMR spectroscopy. |
Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Rycroft, Dr David and Robins, Prof David |
Authors: | Rycroft, D. S., Stirling, I. R., and Robins, D. J. |
Subjects: | Q Science > QD Chemistry |
College/School: | College of Science and Engineering > School of Chemistry |
Journal Name: | Magnetic Resonance in Chemistry |
Publisher: | John Wiley & Sons, Ltd |
ISSN: | 0749-1581 |
ISSN (Online): | 1097-458X |
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