Solving the WAVE function

Blagg, S. L. and Insall, R. H. (2004) Solving the WAVE function. Nature Cell Biology, 6(4), pp. 279-281. (doi:10.1038/ncb0404-279) (PMID:15057236)

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Abstract

SCAR/WAVE proteins are central regulators of cell motility that coordinate actin reorganization through activation of the Arp2/3 complex. Their activity is controlled by a large complex with four other members. A new study contradicts earlier work by suggesting that the entire complex is required for SCAR/WAVE activity at the leading edge.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Insall, Professor Robert
Authors: Blagg, S. L., and Insall, R. H.
College/School:College of Medical Veterinary and Life Sciences > Institute of Cancer Sciences
Journal Name:Nature Cell Biology
Publisher:Nature Publishing Group
ISSN:1465-7392
ISSN (Online):1476-4679

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