Neural correlates of evidence accumulation during value-based decisions revealed via simultaneous EEG-fMRI

Pisauro, M. A., Fouragnan, E., Retzler, C. and Philiastides, M. G. (2017) Neural correlates of evidence accumulation during value-based decisions revealed via simultaneous EEG-fMRI. Nature Communications, 8, 15808. (doi:10.1038/ncomms15808) (PMID:28598432) (PMCID:PMC5472767)

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Abstract

Current computational accounts posit that, in simple binary choices, humans accumulate evidence in favour of the different alternatives before committing to a decision. Neural correlates of this accumulating activity have been found during perceptual decisions in parietal and prefrontal cortex; however the source of such activity in value-based choices remains unknown. Here we use simultaneous EEG-fMRI and computational modelling to identify EEG signals reflecting an accumulation process and demonstrate that the within- and across-trial variability in these signals explains fMRI responses in posterior-medial frontal cortex. Consistent with its role in integrating the evidence prior to reaching a decision, this region also exhibits task-dependent coupling with the ventromedial prefrontal cortex and the striatum, brain areas known to encode the subjective value of the decision alternatives. These results further endorse the proposition of an evidence accumulation process during value-based decisions in humans and implicate the posterior-medial frontal cortex in this process.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Retzler, Mr Christopher and Pisauro, Dr Michele Andrea and Fouragnan, Dr Elsa and Philiastides, Dr Marios
Authors: Pisauro, M. A., Fouragnan, E., Retzler, C., and Philiastides, M. G.
College/School:College of Medical Veterinary and Life Sciences > Institute of Neuroscience and Psychology
Journal Name:Nature Communications
Publisher:Nature Publishing Group
ISSN:2041-1723
ISSN (Online):2041-1723
Copyright Holders:Copyright © 2017 The Authors
First Published:First published in Nature Communications 8:15808
Publisher Policy:Reproduced under a Creative Commons License

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
653861Spatiotemporal characterization of value judgments and reward processing in the human brainMarios PhiliastidesBiotechnology and Biological Sciences Research Council (BBSRC)BB/J015393/2INP - CENTRE FOR COGNITIVE NEUROIMAGING
654411Neural correlates of learning and confidence during decision making and their utility in developing "intelligent technologies".Marios PhiliastidesEconomic & Social Research Council (ESRC)ES/L012995/1INP - CENTRE FOR COGNITIVE NEUROIMAGING