Transcriptional regulation of Rho GTPase signaling

Croft, D. R. and Olson, M. F. (2011) Transcriptional regulation of Rho GTPase signaling. Transcription, 2(5), pp. 211-215. (doi: 10.4161/trns.2.5.16904) (PMID:22231116) (PMCID:PMC3265777)

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Abstract

Signaling through the Rho family of small GTPases regulates a variety of cellular processes via changes in the actin cytoskeleton. Here we discuss recent findings that show the transcription factor p53 regulates the expression of several Rho pathway signaling molecules, and how mutation of p53 in cancer dramatically alters signaling output through this pathway.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Croft, Dr Daniel and Olson, Professor Michael
Authors: Croft, D. R., and Olson, M. F.
College/School:College of Medical Veterinary and Life Sciences > School of Cancer Sciences
Journal Name:Transcription
Publisher:Taylor & Francis
ISSN:2154-1264
ISSN (Online):2154-1272
Published Online:05 September 2011

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