Comparing methods of assessing dog rabies vaccination coverage in rural and urban communities in Tanzania

Sambo, M. et al. (2017) Comparing methods of assessing dog rabies vaccination coverage in rural and urban communities in Tanzania. Frontiers in Veterinary Science, 4, 33. (doi:10.3389/fvets.2017.00033) (PMID:28352630) (PMCID:PMC5348529)

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Abstract

Rabies can be eliminated by achieving comprehensive coverage of 70% of domestic dogs during annual mass vaccination campaigns. Estimates of vaccination coverage are, therefore, required to evaluate and manage mass dog vaccination programs; however, there is no specific guidance for the most accurate and efficient methods for estimating coverage in different settings. Here, we compare post-vaccination transects, school-based surveys, and household surveys across 28 districts in southeast Tanzania and Pemba island covering rural, urban, coastal and inland settings, and a range of different livelihoods and religious backgrounds. These approaches were explored in detail in a single district in northwest Tanzania (Serengeti), where their performance was compared with a complete dog population census that also recorded dog vaccination status. Post-vaccination transects involved counting marked (vaccinated) and unmarked (unvaccinated) dogs immediately after campaigns in 2,155 villages (24,721 dogs counted). School-based surveys were administered to 8,587 primary school pupils each representing a unique household, in 119 randomly selected schools approximately 2 months after campaigns. Household surveys were conducted in 160 randomly selected villages (4,488 households) in July/August 2011. Costs to implement these coverage assessments were $12.01, $66.12, and $155.70 per village for post-vaccination transects, school-based, and household surveys, respectively. Simulations were performed to assess the effect of sampling on the precision of coverage estimation. The sampling effort required to obtain reasonably precise estimates of coverage from household surveys is generally very high and probably prohibitively expensive for routine monitoring across large areas, particularly in communities with high human to dog ratios. School-based surveys partially overcame sampling constraints, however, were also costly to obtain reasonably precise estimates of coverage. Post-vaccination transects provided precise and timely estimates of community-level coverage that could be used to troubleshoot the performance of campaigns across large areas. However, transects typically overestimated coverage by around 10%, which therefore needs consideration when evaluating the impacts of campaigns. We discuss the advantages and disadvantages of these different methods and make recommendations for how vaccination campaigns can be better monitored and managed at different stages of rabies control and elimination programs.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Johnson, Dr Paul and Lembo, Dr Tiziana and Cleaveland, Professor Sarah and Hotopp, Ms Karen and Hampson, Dr Katie and Townsend, Dr Sunny
Authors: Sambo, M., Johnson, P. C.D., Hotopp, K., Changalucha, J., Cleaveland, S., Kazwala, R., Lembo, T., Lugelo, A., Lushasi, K., Maziku, M., Mbunda, E., Mtema, Z., Sikana, L., Townsend, S. E., and Hampson, K.
College/School:College of Medical Veterinary and Life Sciences > Institute of Biodiversity Animal Health and Comparative Medicine
Journal Name:Frontiers in Veterinary Science
Publisher:Frontiers Media
ISSN:2297-1769
ISSN (Online):2297-1769
Published Online:14 March 2017
Copyright Holders:Copyright © 2017 Sambo, Johnson, Hotopp, Changalucha, Cleaveland, Kazwala, Lembo, Lugelo, Lushasi, Maziku, Mbunda, Mtema, Sikana, Townsend and Hampson
First Published:First published in Frontiers in Veterinary Science 4:33
Publisher Policy:Reproduced under a Creative Commons License

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
569041Hierarchical epidemiology: the spread and persistence of infectious diseases in complex landscapesKatie HampsonWellcome Trust (WELLCOME)095787/Z/11/ZRI BIODIVERSITY ANIMAL HEALTH & COMPMED