Trifluoromethylthiolation of aromatic substrates using thiophosgene—fluoride salt reagents, and formation of byproducts with multi-carbon chains

Tavener, S. J., Adams, D. J. and Clark, J. H. (1999) Trifluoromethylthiolation of aromatic substrates using thiophosgene—fluoride salt reagents, and formation of byproducts with multi-carbon chains. Journal of Fluorine Chemistry, 95(1-2), pp. 171-176. (doi: 10.1016/S0022-1139(99)00063-9)

Abstract

Reaction of potassium fluoride or tetramethylammonium fluoride with thiophosgene leads to the formation of a nucleophilic source of trifluoromethanethiolate, suitable for the preparation of trifluoromethyl aryl sulfides from activated haloaromatics. Analysis of the by-products in the system demonstrates that complex molecules with up to C4 chains may be formed by the reaction of fluoride salts with thiophosgene.

• Item Type: Articles
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Adams, Dave
• Authors: Tavener, S. J., Adams, D. J., and Clark, J. H.
• College/School: College of Science and Engineering > School of Chemistry
• Journal Name: Journal of Fluorine Chemistry
• Publisher: Elsevier
• ISSN: 0022-1139
• ISSN (Online): 1873-3328
• Published Online: 07 January 2000