Influence of Molecular Structure on the Gelation Behaviour of Fmoc-Dipeptides

Adams, D. J. , Butler, M. F., Kirkland, M., Mullen, L., Frith, W. J., Co, A., Leal, G. L., Colby, R. H. and Giacomin, A. J. (2008) Influence of Molecular Structure on the Gelation Behaviour of Fmoc-Dipeptides. In: The XVth International Congress on Rheology: The Society of Rheology 80th Annual Meeting, Monterey, CA, 3-8 Aug 2008, pp. 555-557. ISBN 9780735405493 (doi:10.1063/1.2964763)

Abstract

We show that the gel strength of the hydrogels formed from a range of Fmoc‐dipeptides is determined by the constituent amino acids, with the final gel strength being linked to the overall hydrophobicity of the Fmoc‐dipeptide. Gelation is triggered using glucono‐δ‐lactone, which controllably lowers the pH, allowing the gel properties to be followed with time. This can be observed both in terms of the development of the gel strength with time using rheology and of the microstructure of the networks as observed by cryo‐SEM.

• Item Type: Conference Proceedings
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Adams, Dave
• Authors: Adams, D. J., Butler, M. F., Kirkland, M., Mullen, L., Frith, W. J., Co, A., Leal, G. L., Colby, R. H., and Giacomin, A. J.
• College/School: College of Science and Engineering > School of Chemistry
• ISSN: 0094-243X
• ISBN: 9780735405493
• Copyright Holders: Copyright © 2008 American Institute of Physics
• Publisher Policy: Reproduced in accordance with the copyright policy of the publisher