Armitage, E. G. and Ciborowski, M. (2017) Applications of metabolomics in cancer studies. In: Sussulini, A. (ed.) Metabolomics: From Fundamentals to Clinical Applications. Series: Advances in experimental medicine and biology, 965. Springer International Publishing, pp. 209-234. ISBN 9783319476551 (doi: 10.1007/978-3-319-47656-8_9)
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Abstract
Since the start of metabolomics as a field of research, the number of studies related to cancer has grown to such an extent that cancer metabolomics now represents its own discipline. In this chapter, the applications of metabolomics in cancer studies are explored. Different approaches and analytical platforms can be employed for the analysis of samples depending on the goal of the study and the aspects of the cancer metabolome being investigated. Analyses have concerned a range of cancers including lung, colorectal, bladder, breast, gastric, oesophageal and thyroid, amongst others. Developments in these strategies and methodologies that have been applied are discussed, in addition to exemplifying the use of cancer metabolomics in the discovery of biomarkers and in the assessment of therapy (both pharmaceutical and nutraceutical). Finally, the application of cancer metabolomics in personalised medicine is presented.
| Item Type: | Book Sections |
|---|---|
| Status: | Published |
| Glasgow Author(s) Enlighten ID: | Armitage, Dr Emily Grace |
| Authors: | Armitage, E. G., and Ciborowski, M. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Infection & Immunity |
| Publisher: | Springer International Publishing |
| ISBN: | 9783319476551 |
| Published Online: | 29 January 2017 |
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