Poly[2-(methacryloyloxy)ethylphosphorylcholine]-coated iron oxide nanoparticles: synthesis, colloidal stability and evaluation for stem cell labelling

Peacock, A. K., Cauët, S. I., Taylor, A., Murray, P., Williams, S. R., Weaver, J. V. M., Adams, D. J. and Rosseinsky, M. J. (2012) Poly[2-(methacryloyloxy)ethylphosphorylcholine]-coated iron oxide nanoparticles: synthesis, colloidal stability and evaluation for stem cell labelling. Chemical Communications, 48(75), pp. 9373-9375. (doi: 10.1039/C2CC34420C) (PMID:22895154)

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Abstract

Poly[2-(methacryloyloxy)ethylphosphorylcholine]-coated SPIONs were prepared through ATRP and amidation coupling reactions. The coated SPIONs exhibited high stability and re-dispersability in phosphate buffered saline and uptake in a stem cell line, with high T2 relaxivity.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Adams, Dave
Authors: Peacock, A. K., Cauët, S. I., Taylor, A., Murray, P., Williams, S. R., Weaver, J. V. M., Adams, D. J., and Rosseinsky, M. J.
College/School:College of Science and Engineering > School of Chemistry
Journal Name:Chemical Communications
Publisher:Royal Society of Chemistry
ISSN:1359-7345
ISSN (Online):1364-548X
Published Online:26 July 2012

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