Encystation-specific vesicles in Giardia: a primordial Golgi or just another secretory compartment?

Marti, M. and Hehl, A. B. (2003) Encystation-specific vesicles in Giardia: a primordial Golgi or just another secretory compartment? Trends in Parasitology, 19(10), pp. 440-446. (doi:10.1016/S1471-4922(03)00201-0) (PMID:14519581)

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Abstract

Giardia intestinalis is better known to cause diarrheal disease than to be the object of basic research in cell biology. However, this is about to change: the unique biology of this parasite and a genome project combine to earn this amitochondriate a place among the better-known model organisms. One consequence of its phylogenetic status is that Giardia has at the same time highly specialized traits, and basic features such as an apparently Golgi-less secretory system. This article discusses the unique nature of the Giardia secretory system and implications of novel insights in the context of eukaryotic endomembrane organization and evolution.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Marti, Professor Matthias
Authors: Marti, M., and Hehl, A. B.
College/School:College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
Journal Name:Trends in Parasitology
Publisher:Elsevier
ISSN:1471-4922
ISSN (Online):1471-5007
Published Online:14 August 2003

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