Signal-mediated export of proteins from the malaria parasite to the host erythrocyte

Marti, M. , Baum, J., Rug, M., Tilley, L. and Cowman, A. F. (2005) Signal-mediated export of proteins from the malaria parasite to the host erythrocyte. Journal of Cell Biology, 171(4), pp. 587-592. (doi:10.1083/jcb.200508051) (PMID:16301328) (PMCID:PMC2171567)

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Abstract

Intracellular parasites from the genus Plasmodium reside and multiply in a variety of cells during their development. After invasion of human erythrocytes, asexual stages from the most virulent malaria parasite, P. falciparum, drastically change their host cell and export remodelling and virulence proteins. Recent data demonstrate that a specific NH2-terminal signal conserved across the genus Plasmodium plays a central role in this export process.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Marti, Professor Matthias
Authors: Marti, M., Baum, J., Rug, M., Tilley, L., and Cowman, A. F.
College/School:College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
Journal Name:Journal of Cell Biology
Publisher:Rockefeller University Press
ISSN:0021-9525
ISSN (Online):1540-8140
Copyright Holders:Copyright © 2005 The Rockefeller University Press
First Published:First published in Journal of Cell Biology 171(4):587-592
Publisher Policy:Reproduced under a Creative Commons License

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