Probing gelation ability for a library of dipeptide gelators

Awhida, S., Draper, E. R. , McDonald, T. O. and Adams, D. J. (2015) Probing gelation ability for a library of dipeptide gelators. Journal of Colloid and Interface Science, 455, pp. 24-31. (doi: 10.1016/j.jcis.2015.05.032) (PMID:26047582)

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Functionalised dipeptides are a class of interesting and useful low molecular weight hydrogelators. Here, we report a significantly expanded library of materials, including dipeptides conjugated to carbazole, phenanthracene, anthracene, pyrene and substituted naphthalenes. We assess the effect of using two different gelation methods; a pH-switch and a solvent switch on the gelation behaviour and properties of the dipeptides. Importantly, we investigate the relationship between the structure of these dipeptides and their ability to form gels. From an analysis of the gelation ability of all these dipeptides, it is clear that those containing a phenylalanine as either of the constituent amino acids are much more likely to lead to a gelator being formed as opposed to using non-aromatic amino acids only.

Item Type:Articles
Glasgow Author(s) Enlighten ID:Draper, Emily and Adams, Dave
Authors: Awhida, S., Draper, E. R., McDonald, T. O., and Adams, D. J.
College/School:College of Science and Engineering > School of Chemistry
Journal Name:Journal of Colloid and Interface Science
ISSN (Online):1095-7103
Published Online:23 May 2015

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