Postma, T.M. and Liskamp, R.M.J. (2016) Triple-targeting Gram-negative selective antimicrobial peptides capable of disrupting the cell membrane and lipid A biosynthesis. RSC Advances, 6(70), pp. 65418-65421. (doi: 10.1039/c6ra11550k)
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Abstract
Early lipid A biosynthesis is a potential antimicrobial target as this is an essential component of lipid A producing Gram-negative bacteria. Herein, we introduce a potent and highly synergistic Gram-negative selective triple-targeting antimicrobial peptide. The peptide contains a dual lipid A biosynthesis inhibiting sequence and an antimicrobial sequence.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Liskamp, Professor Robert and Postma, Dr Tobias |
| Authors: | Postma, T.M., and Liskamp, R.M.J. |
| College/School: | College of Science and Engineering > School of Chemistry |
| Journal Name: | RSC Advances |
| Publisher: | Royal Society of Chemistry |
| ISSN: | 2046-2069 |
| ISSN (Online): | 2046-2069 |
| Published Online: | 04 July 2016 |
| Copyright Holders: | Copyright © 2016 Royal Society of Chemistry |
| First Published: | First published in RSC Advances 6(70):65418-65421 |
| Publisher Policy: | Reproduced in accordance with the copyright policy of the publisher |
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