Harrison, N., Field, J. R., Quondamatteo, F., Curtin, W., McHugh, P. E. and Mc Donnell, P. (2014) Preclinical trial of a novel surface architecture for improved primary fixation of cementless orthopaedic implants. Clinical Biomechanics, 29(8), pp. 861-868. (doi: 10.1016/j.clinbiomech.2014.07.007) (PMID:25156456)
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Abstract
BACKGROUND: A new surface architecture for cementless orthopaedic implants (OsteoAnchor), which incorporates a multitude of tiny anchor features for enhancing primary fixation, was tested in an ovine hemi-arthroplasty pilot study. METHODS: Test animals were implanted with a hip stem component incorporating the OsteoAnchor surface architecture produced using additive layer manufacturing and control animals were implanted with stems containing a standard plasma sprayed titanium coating. FINDINGS: Intra-operative surgeon feedback indicated that superior primary fixation was achieved for the OsteoAnchor stems and rapid return to normal gait and load bearing was observed post-operation. Following a 16-week recovery time, histological evaluation of the excised femurs revealed in-growth of healthy bone into the porous structure of the OsteoAnchor stems. Bone in-growth was not achieved for the plasma sprayed stems. INTERPRETATION: These results indicate the potential for the OsteoAnchor surface architecture to enhance both the initial stability and long term lifetime of cementless orthopaedic implants.
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Quondamatteo, Prof Fabio |
Authors: | Harrison, N., Field, J. R., Quondamatteo, F., Curtin, W., McHugh, P. E., and Mc Donnell, P. |
College/School: | College of Medical Veterinary and Life Sciences > School of Life Sciences |
Journal Name: | Clinical Biomechanics |
Publisher: | Elsevier |
ISSN: | 0268-0033 |
ISSN (Online): | 1879-1271 |
Published Online: | 10 August 2014 |
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