In Vitro. antimicrobial activity of some Libyan medicinal plant extracts

Abdelah Bogdadi, H. A., Kokoska, L., Havlik, J. , Kloucek, P., Rada, V. and Vorisek, K. (2007) In Vitro. antimicrobial activity of some Libyan medicinal plant extracts. Pharmaceutical Biology, 45(5), pp. 386-391. (doi:10.1080/13880200701215026)

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Abstract

In vitro. antimicrobial activity of 32 extracts (ethanol, hexane, chloroform, and methanol) from eight different Libyan medicinal plants, namely Artemisia herba-alba. Asso (Compositae), Globularia alypum. L. (Globulariaceae), Helichrysum stoechas., DC. (Compositae), Peganum harmala. L. (Zygophyllaceae), Polygonum equisetiforme. Sibth. & Sm. (Polygonaceae), Pulicaria crispa. (Forssk.) Oliv. (Compositae), Rosmarinus officinalis. L. (Labiatae), and Thymus capitatus. Hoffmanns & Link. (Labiatae), was determined against seven bacteria and one yeast strain using the broth microdilution method. The results show that all plants tested possessed antimicrobial activity against at least one of the examined strains at a concentration ≤8 mg/ml. The extracts from H. stoechas., P. equisetiforme., P. crispa., R. officinalis., and T. capitatus. exhibited strongest activity against Gram-positive bacteria with minimum inhibitory concentrations (MICs) ranging from 0.5 to 8 mg/ml. Only a few extracts showed inhibitory activity against Gram-negative strains in this test, whereas those of the H. stoechas. and P. harmala. were among the strongest ones (MICs range 4–8 mg/ml). High anticandidal activity was observed for P. harmala., P. crispa., and T. capitatus., with MICs ranging from 0.25 to 1 mg/ml.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Havlik, Dr Jaroslav
Authors: Abdelah Bogdadi, H. A., Kokoska, L., Havlik, J., Kloucek, P., Rada, V., and Vorisek, K.
College/School:College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing
Journal Name:Pharmaceutical Biology
Publisher:Taylor and Francis
ISSN:1388-0209
ISSN (Online):1744-5116

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