Continuous parallel ESI-MS analysis of reactions carried out in a bespoke 3D printed device

Mathieson, J. S., Rosnes, M. H., Sans, V., Kitson, P. J. and Cronin, L. (2013) Continuous parallel ESI-MS analysis of reactions carried out in a bespoke 3D printed device. Beilstein Journal of Nanotechnology, 4, pp. 285-291. (doi: 10.3762/bjnano.4.31) (PMID:23766951) (PMCID:PMC3678396)

Abstract

Herein, we present an approach for the rapid, straightforward and economical preparation of a tailored reactor device using three-dimensional (3D) printing, which can be directly linked to a high-resolution electrospray ionisation mass spectrometer (ESI-MS) for real-time, in-line observations. To highlight the potential of the setup, supramolecular coordination chemistry was carried out in the device, with the product of the reactions being recorded continuously and in parallel by ESI-MS. Utilising in-house-programmed computer control, the reactant flow rates and order were carefully controlled and varied, with the changes in the pump inlets being mirrored by the recorded ESI-MS spectra.

• Item Type: Articles
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Kitson, Dr Philip and Rosnes, Dr Mali and Mathieson, Dr Jennifer and Cronin, Professor Lee and Sans Sangorrin, Dr Victor
• Authors: Mathieson, J. S., Rosnes, M. H., Sans, V., Kitson, P. J., and Cronin, L.
• College/School: College of Science and Engineering > School of Chemistry
• Journal Name: Beilstein Journal of Nanotechnology
• Publisher: Beilstein-Institut
• ISSN: 2190-4286
• ISSN (Online): 2190-4286
• Copyright Holders: Copyright © 2013 Mathieson et al.
• First Published: First published in Beilstein Journal of Nanotechnology 4:285-291
• Publisher Policy: Reproduced under a creative commons license