Pathogenesis of fungal infections in cystic fibrosis

Williams, C., Ranjendran, R. and Ramage, G. (2016) Pathogenesis of fungal infections in cystic fibrosis. Current Fungal Infection Reports, 10(4), pp. 163-169. (doi:10.1007/s12281-016-0268-z) (PMID:28035247) (PMCID:PMC5155017)

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Abstract

For a long time, the microbiology of cystic fibrosis has been focussed on Pseudomonas aeruginosa and associated Gram-negative pathogens. An increasing body of evidence has been compiled demonstrating an important role for moulds and yeasts within this complex patient group. Whether or not fungi are active participants, spectators or transient passersby remain to be elucidated. However, functionally, they do appear to play a contributory role in pathogenesis, albeit we do not know if this is a direct or indirect effect. The following review examines some of the key evidence for the role of fungi in CF pathogenesis.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Ramage, Professor Gordon and Williams, Dr Craig
Authors: Williams, C., Ranjendran, R., and Ramage, G.
College/School:College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing > Dental School
Journal Name:Current Fungal Infection Reports
Publisher:Current Medicine Group
ISSN:1936-3761
ISSN (Online):1936-377X
Published Online:07 December 2016
Copyright Holders:Copyright © 2016 The Authors
First Published:First published in Current Fungal Infection Reports 10(4):163-169
Publisher Policy:Reproduced under a Creative Commons License

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