The luminance–response function of the human photopic electroretinogram: a mathematical model

Hamilton, R., Bees, M.A., Chaplin, C.A. and McCulloch, D.L. (2007) The luminance–response function of the human photopic electroretinogram: a mathematical model. Vision Research, 47(23), pp. 2968-2972. (doi: 10.1016/j.visres.2007.04.020)

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Publisher's URL: http://dx.doi.org/10.1016/j.visres.2007.04.020

Abstract

The luminance–response function of the brief flash full-field photopic electroretinogram (ERG) rises to a peak before falling to a sub-maximal plateau – the 'photopic hill'. The combination of on- and off-responses inherent in the brief flash photopic ERG suggests that this luminance–response function could be modelled by the sum of a Gaussian function and a logistic growth function. Photopic ERGs to a luminance series of brief flashes against three different background luminances recorded from seven healthy adults showed the characteristic 'photopic hill' function for b-wave amplitudes which were satisfactorily fitted with the sum of a Gaussian curve and a logistic growth curve. As background luminance increased, both components shifted to the right on the luminance axis. The Gaussian component increased in amplitude while the logistic growth function component decreased in amplitude. The luminance–response function of a complete congenital stationary night blindness patient had almost no logistic growth component.

Item Type:Articles
Refereed:Yes
Glasgow Author(s) Enlighten ID:Bees, Dr Martin
Authors: Hamilton, R., Bees, M.A., Chaplin, C.A., and McCulloch, D.L.
College/School:College of Science and Engineering > School of Mathematics and Statistics > Mathematics
Journal Name:Vision Research
Publisher:Pergamon
ISSN:0042-6989
ISSN (Online):1878-5646
Published Online:24 September 2007

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