Rotaxanes of cyclic peptides

Aucagne, V., Leigh, D. A., Lock, J. S. and Thomson, A. R. (2006) Rotaxanes of cyclic peptides. Journal of the American Chemical Society, 128(6), pp. 1784-1785. (doi:10.1021/ja057206q) (PMID:16464065)

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Abstract

The synthesis of rotaxanes derived from the synthetic peptide macrocycles cyclo(l-ProGly)4 and cyclo(l-ProGly)5 and diammonium threads is described. [2]Rotaxanes are formed in good yields (56−63%), despite the disruption of internal amide−amide hydrogen bonding in the macrocycles.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Thomson, Dr Drew
Authors: Aucagne, V., Leigh, D. A., Lock, J. S., and Thomson, A. R.
College/School:College of Science and Engineering > School of Chemistry
Journal Name:Journal of the American Chemical Society
Publisher:American Chemical Society
ISSN:0002-7863
ISSN (Online):1520-5126
Published Online:19 January 2006

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